- by Michelangelo Di LuzioBackground: It is well documented in the scientific literature that obsessive-compulsive disorder (OCD) and various eating disorders may present overlapping psychopathological traits. Exploring these aspects could help to identify underlying features that connect different diagnostic categories. However, evidence is lacking regarding certain less-studied eating disorders, such as avoidant/restrictive food intake disorder (ARFID). The aim of this review is to investigate the presence of…
- by Marina Serrano-OrtizObsessive-compulsive disorder (OCD) is a frequent condition in the pediatric population, with significant clinical impact and high comorbidity. This umbrella review aimed to synthesize evidence from systematic reviews and meta-analyses on the efficacy of interventions for OCD in individuals under 18 years of age. Searches were conducted in five electronic databases up to July 2025. A total of 28 systematic reviews and meta-analyses published between 2003 and 2025 were included, assessing the…
- by Matthias PallamarBackground/Objectives: Juvenile osteochondritis dissecans (JOCD) of the knee is commonly treated using conservative or joint-preserving surgical techniques. While clinical outcomes are generally favorable, the risk of early cartilage degeneration remains unclear. Joint space width (JSW) on weight-bearing radiographs serves as an indirect marker of cartilage health. Artificial intelligence (AI)-based JSW assessment may enable sensitive and reproducible detection of early degenerative changes….
- by Lyndon BooneCONCLUSION: Despite high methodological heterogeneity and small sample sizes in the primary literature, these findings underscore the potential of neuroimaging to inform patient selection and clarify mechanisms of OCD lesioning therapy. Network analyses may provide a framework for considering novel therapeutic targets. Future prospective research should verify the role of the anterior cingulate cortex in predicting treatment response, and further explore mechanistic changes in distributed brain…
- by Acácio Moreira-NetoNo abstract
- by Steffen MassanneckAlthough virtual reality has been used in psychotherapy since the 1990s, research and clinical practice have focused strongly on its application in exposure therapy. Over the last decade, the emergence of a new generation of virtual reality devices has led to a surge in virtual reality applications, which are also gaining traction in other areas of mental health care. The use of virtual reality in children and adolescent psychotherapy is especially interesting because it provides engaging and…
- by Carla P LoureiroAcceptance and Commitment Therapy (ACT) has shown promise as a treatment for obsessive-compulsive disorder (OCD) in clinical trials; however, its cross-cultural applicability remains underexplored. This systematic review and meta-analysis assessed ACT's global efficacy across diverse cultural contexts. A comprehensive search of MEDLINE, Scopus, Web of Science, PsycINFO, Google Scholar, and ClinicalTrials.gov identified 468 records, of which nine randomized controlled trials (RCTs) met inclusion…
- by Gabriella Restifo-BernsteinGlutamatergic dysfunction in cortico-striato-thalamo-cortical (CSTC) circuits is a hypothesized cause of obsessive-compulsive disorder (OCD). Numerous proton magnetic resonance spectroscopy (¹H MRS) studies have examined this question, yet no systematic review has been conducted in unmedicated participants with OCD. We searched PubMed, Web of Science, and Embase for ¹H MRS studies examining glutamate (Glu) and the related metabolites glutamine (Gln) and γ-aminobutyric acid (GABA), which are…
- by Yihui ChengCONCLUSIONS: This comprehensive review of up-to-date neurobiological studies of individuals with BDD reveals differences in brain structure and functionality compared with control participants. The proposed neurocircuitry model expands on the previous understanding of BDD neurobiology and elucidates the interconnection between the visual processing, temporal-limbic, and frontostriatal networks and their clinical implications. This review provides theoretical support for future neuromodulation…
- by Lenka OttingerováChairwork refers to a set of experiential psychotherapeutic interventions in which the physical positioning of the chairs facilitates internal and interpersonal dialogue. This study is an attempt to rectify the lack of a systematic review of the research on the effectiveness of Chairwork by offering a systematic review of randomized controlled trials (RCTs) that assess the effectiveness of Chairwork-based interventions used in various psychotherapeutic approaches for the treatment of…
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